Cleaning is the necessary first step of any disinfection process. Cleaning
removes organic matter, salts, and visible soils, all of which interfere with
microbial inactivation. The physical action of scrubbing with detergents and
surfactants and rinsing with water removes substantial numbers of
microorganisms. If a surface is not cleaned first, the success of the disinfection
process can be compromised. Removal of all visible blood and inorganic and
organic matter can be as critical as the germicidal activity of the disinfecting
agent. When a surface cannot be cleaned adequately, it should be protected
with barriers.
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